Hathairat Thananchai, Dr. Phil.
Assistant professor
Department chair
hathairat.t@cmu.ac.th
Office
50th Anniversary building, Room 716, Faculty of Medicine
Research interest
” I am interested in host-pathogen interaction especially innate immune response. My research focuses on Streptococcus suis infection, one of the most important zoonotic pathogens worldwide. Although several virulence factors have been identified, the pathogenesis of S. suis infection remains poorly understood. My present work mainly concentrates on the investigation of pyroptotic mechanism caused by different clinical isolates of S. suis. Meanwhile, I have also developed a CRISPR-Cas12a based assay for the rapid detection of S. suis in a clinical specimen.
The other area of my interest is cancer immunotherapy. In collaboration with the Division of Hematology, Department of Internal Medicine, our aim is to develop CAR-T cell for treating patients with leukemia or lymphoma. We also aim to identify neoantigen in cancer patients.”
Short biography
Dr.Hathairat Thananchai is an Assistant Professor in immunology in the Department of Microbiology. Her Bachelor’s degree is in medical technology from Chiang Mai University and she got a Master of Science in Microbiology from Mahidol University. She received her Doctor of Philosophy (D.Phil) in Clinical Medicine from the University of Oxford, United Kingdom under the supervision of Professor Sarah Rowland-Jones and Professor Tao Dong. Her doctoral work was about the role of NK cell and their receptors in HIV infection.
Field of research
Host-microbe interactions, Immunity to infection, Tumor immunology
Current projects
1. Induction of pyroptotic cell death by Streptococcus suis
2. Development of CRISPR-Cas12a-based assay for rapid detection of Streptococcus suis