Publication:
J Infect Dis 2011; 28: 36-44.
Abstract:
Background: Conducting surveillance for multidrug-resistant organisms leads to identify changes in the pathogens causing HAIs of specific sites, and the antimicrobial susceptibility patterns. This surveillance study aimed to characterize the pattern of nosocomial multidrug-resistant pathogens
Methods: Clinical laboratory reports from Chiang Mai University hospital were reviewed from 2006 to 2009.
Results: During the 4-year period, gram-negative bacteria were the majority of clinical isolates. A. baumannii was the most common pathogen isolated from sputum. E. coli was the most common pathogen isolated from blood and urine. Carbapenem resistant among A. baumanii isolates was 67.1%, 74.2%, 68.9%, and 74.2% in 2006, 2007, 2008, and 2009, respectively.
Carbapenem resistant among P. aeruginosa was 35.0%, 33.8%, 27.0%, and 26.8% in 2006, 2007, 2008, and 2009, respectively. Extended-spectrum ?-lactamase producing strains were accounted for 35.2% and 49.2% among E. coli and K. pneumoniae, respectivelyin 2006 and 53.2% and 56.5% in 2009. Gram-positive bacteria were accounted for 25% of all isolates for all 4 years. S. aureus and Enterococci were the most common gram-positive pathogens. Among S. aureus, 35% and 44% were methicillin-resistant strains in 2006 and 2009, respectively.
Conclusions: The surveillance data showed that gram-negative bacteria are the major problems in our hospital. Multidrug-resistant Acinetobacter baumannii is a problem concerned. Continuing surveillance is essential to monitor the trend of these multidrug-resistant bacteria.
